产品货号：
Z32275
中文名称：
APAF1抗体
英文名称：
Anti-APAF1 Antibody (Clone#2E10)
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-APAF1 Antibody (Clone#2E10) |
| 指标别名 | APAF 1;APAF1;CED4;DKFZp781B1145;KIAA0413 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | APAF1 |
| 克隆号 | 2E10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | A peptide corresponding to amino acids near the carboxy terminus of human Apaf1. |
| 计算分子量 | 142kDa |
| 成分 | Apaf-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Apaf-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Apaf-1 monoclonal antibody can be stored at -20℃,stable for one year. |
| 背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.The mammalian homologous of the key cell death gene CED-4 in C.elegans was identified recently from human and mouse and designated Apaf1 for apoptosis protease-activating factor 1.Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3),which leads to caspase-9 activation.Activated caspase-9 in turn cleaves and activates caspase-3 that is one of the key proteases,being responsible for the proteolytic cleavage of many key proteins in apoptosis.Apaf1 can also associate with caspase-4 and caspase-8.Apaf1 transcript is ubiquitously expressed in human tissues. |
| Uniprot ID | O14727 |
| 基因名全称 | Apoptotic peptidase activating factor 1 |
| 蛋白名全称 | Apoptotic peptidase activating factor 1 |
| 推荐稀释比 | Apaf1 antibody can be used for detection of Apaf1 by Western blot at 0.25 ～ 0.5mg/mL.A 130kDa band should be detected.Antibody can also be used for immunohistochemistry starting at 0.5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
相关搜索：APAF1抗体，APAF1单抗，Anti-APAF1 Antibody (Clone#2E10)